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The use of systemic and topical fluoroquinolones. Pediatrics 2011 Oct;128(4):e1034-45

Date

09/29/2011

Pubmed ID

21949152

DOI

10.1542/peds.2011-1496

Scopus ID

2-s2.0-80053477373 (requires institutional sign-in at Scopus site)   120 Citations

Abstract

Appropriate prescribing practices for fluoroquinolones are essential as evolving resistance patterns are considered, additional treatment indications are identified, and the toxicity profile of fluoroquinolones in children becomes better defined. Earlier recommendations for systemic therapy remain; expanded uses of fluoroquinolones for the treatment of certain infections are outlined in this report. Although fluoroquinolones are reasonably safe in children, clinicians should be aware of the specific adverse reactions. Use of fluoroquinolones in children should continue to be limited to treatment of infections for which no safe and effective alternative exists.

Author List

Bradley JS, Jackson MA, Committee on Infectious Diseases, American Academy of Pediatrics

Author

Rodney E. Willoughby MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Administration, Oral
Administration, Topical
Animals
Anti-Bacterial Agents
Bacterial Infections
Drug Resistance, Bacterial
Fluoroquinolones
Humans