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Invasive aspergillosis of paranasal tissues in children with malignancies. J Pediatr 1983 Jul;103(1):49-53

Date

07/01/1983

Pubmed ID

6575168

DOI

10.1016/s0022-3476(83)80774-4

Abstract

Paranasal aspergillosis was encountered in five children with relapsed malignancies. All had received broad-spectrum antibiotics within two weeks of development of aspergillosis, and all had absolute granulocyte counts less than 200/mm3 for at least three weeks. None had received prior antifungal therapy. There was an average delay of eight days before the correct diagnosis was established by either biopsy or culture. These data emphasize the need to obtain surveillance cultures of the upper respiratory tract passages in severely neutropenic patients receiving prolonged antibiotic therapy, and raise a question concerning prophylactic use of antifungal therapy in this group.

Author List

Berkow RL, Weisman SJ, Provisor AJ, Weetman RM, Baehner RL

Author

Steven J. Weisman MD Professor in the Anesthesiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Anti-Bacterial Agents
Aspergillosis
Child
Child, Preschool
Humans
Leukemia, Lymphoid
Male
Neutropenia
Paranasal Sinus Diseases
Time Factors
jenkins-FCD Prod-484 8aa07fc50b7f6d102f3dda2f4c7056ff84294d1d