The factors involved in deep brain stimulation infection: a large case series. Stereotact Funct Neurosurg 2014;92(4):227-33
Date
08/07/2014Pubmed ID
25096381DOI
10.1159/000362934Scopus ID
2-s2.0-84906000161 (requires institutional sign-in at Scopus site) 44 CitationsAbstract
BACKGROUND: Deep brain stimulation (DBS) is a proven treatment for various movement disorders resistant to medical management. Complications such as postsurgical infection can negate benefits and increase patient morbidity. We sought to better define risk factors for infection.
METHODS: We performed a review of DBS cases at our institution from January 1996 to June 2011. Information on multiple metrics including surgical complications, procedural complications and infection were entered into a secure online database.
RESULTS: A total of 447 patients received DBS surgery. Twenty-six (5.82%) developed infection sometime after DBS surgery with 9 (2.01%) developing infection within 30 days after the final staged surgery. Operating surgeon (p = 0.012), scalp erosion (p = 0.0001), surgical incision opening time (0.0001) and number of individuals in the operating room (0.0027) were significant in the cumulative infection group.
CONCLUSION: The 30-day infection rate was comparably low to other published studies. Several factors were noted to be significant in the cumulative infection group, but none in the 30-day infection group. Further understanding of infection risk factors is important to optimize patient selection and standardize infection-preventative techniques.
Author List
Tolleson C, Stroh J, Ehrenfeld J, Neimat J, Konrad P, Phibbs FAuthor
Jesse Ehrenfeld MD, MPH Sr Associate Dean, Director, Professor in the Advancing a Healthier Wisconsin Endowment department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedAnti-Infective Agents, Local
Antibiotic Prophylaxis
Chlorhexidine
Comorbidity
Deep Brain Stimulation
Electrodes, Implanted
Female
Humans
Incidence
Infection Control
Male
Middle Aged
Operative Time
Postoperative Period
Povidone-Iodine
Retrospective Studies
Risk Factors
Skin Diseases
Surgical Wound Infection
Wound Closure Techniques
