Faculty Collaboration Database

Racial disparities of liver cancer mortality in Wisconsin. Cancer Causes Control 2019 Dec;30(12):1277-1282

Date

09/19/2019

Pubmed ID

31531799

Pubmed Central ID

PMC6858574

DOI

10.1007/s10552-019-01232-9

Scopus ID

2-s2.0-85073816952 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

PURPOSE: To calculate tract-level estimates of liver cancer mortality in Wisconsin and identify relationships with racial and socioeconomic variables.

METHODS: County-level standardized mortality ratios (SMRs) of liver cancer in Wisconsin were calculated using traditional indirect adjustment methods for cases from 2003 to 2012. Tract-level SMRs were calculated using adaptive spatial filtering (ASF). The tract-level SMRs were checked for correlations to a socioeconomic advantage index (SEA) and percent racial composition. Non-spatial and spatial regression analyses with tract-level SMR as the outcome were conducted.

RESULTS: County-level SMR estimates were shown to mask much of the variance within counties across their tracts. Liver cancer mortality was strongly correlated with the percent of Black residents in a census tract and moderately associated with SEA. In the multivariate spatially-adjusted regression analysis, only Percent Black composition remained significantly associated with an increased liver cancer SMR.

CONCLUSIONS: Using ASF, we developed a high-resolution map of liver cancer mortality in Wisconsin. This map provided details on the distribution of liver cancer that were inaccessible in the county-level map. These tract-level estimates were associated with several racial and socioeconomic variables.

Author List

Bemanian A, Cassidy LD, Fraser R, Laud PW, Saeian K, Beyer KMM

Authors

Amin Bemanian in the CTSI department at Medical College of Wisconsin - CTSI
Kirsten M. Beyer PhD, MPH Professor in the Institute for Health and Equity department at Medical College of Wisconsin
Laura Cassidy PhD Associate Dean, Professor in the Institute for Health and Equity department at Medical College of Wisconsin
Raphael Fraser PhD Assistant Professor in the Medicine department at Medical College of Wisconsin
Purushottam W. Laud PhD Professor in the Institute for Health and Equity department at Medical College of Wisconsin
Kia Saeian MD Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Health Status Disparities
Humans
Liver Neoplasms
Regression Analysis
Wisconsin