Revascularization Strategies in Patients with Chronic Kidney Disease and Acute Coronary Syndromes. Curr Cardiol Rep 2019 Aug 30;21(10):113
Date
09/01/2019Pubmed ID
31471758DOI
10.1007/s11886-019-1213-xScopus ID
2-s2.0-85071680733 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
PURPOSE OF REVIEW: Chronic kidney disease (CKD) is a highly prevalent condition that increases the incidence and complexity of acute coronary syndrome (ACS). The purpose of this review is to summarize current evidence, uncertainties, and opportunities in the management of patients with CKD and ACS, with a focus on revascularization.
RECENT FINDINGS: Patients with CKD have been systematically under-represented or excluded from clinical trials in ACS. Available data, however, demonstrates that although patients with CKD and ACS benefit from revascularization, they are also less likely to receive recommended medical and revascularization therapies when compared to patients with normal kidney function. Despite the increased short-term risk of major morbidity and mortality, patients with CKD and ACS should be considered for an early invasive strategy while also trying to mitigate the risks of procedural related complications. Until evidence emerges from randomized clinical trials, the decision about revascularization strategy should involve multi-disciplinary collaboration, heart team consensus, and patient shared decision-making.
Author List
Klein EC, Kapoor R, Lewandowski D, Mason PJAuthors
David Lewandowski MD Assistant Professor in the Medicine department at Medical College of WisconsinPeter Mason MD Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Acute Coronary SyndromeCoronary Artery Bypass
Humans
Percutaneous Coronary Intervention
Renal Insufficiency, Chronic
Treatment Outcome
