Diagnosis of malignant lymphomas of the nasal cavity, paranasal sinuses and nasopharynx. Laryngoscope 1983 Oct;93(10):1276-80
Date
10/01/1983Pubmed ID
6621224DOI
10.1002/lary.1983.93.10.1276Scopus ID
2-s2.0-0020553228 (requires institutional sign-in at Scopus site) 42 CitationsAbstract
The diagnosis of non-Hodgkin's malignant lymphoma of the nasal cavity, paranasal sinuses, and nasopharynx was made in 15 patients over a 7 year period (nasopharynx, 9; nasal cavity, 3; maxillary sinus, 2; frontal sinus, 1). A wide variety of head and neck symptoms, often characteristic of benign disease, was reported ranging from 2 weeks to 4 months prior to presentation. Of the 15 cases, the original diagnosis was inconclusive in 6; 4 of the 6 required rebiopsy, while the diagnosis in the other 2 was confirmed on further pathologic consultation. Tissue marker studies, which have recently become available, were performed in 7 cases and were crucial in the diagnosis of 2. B-cell lymphoma was diagnosed in the 7 patients who had tissue marker studies. Five patients had palpable cervical nodes, and none had distant adenopathy or masses. With further staging, 4 of the 15 patients were found to have disseminated disease. The paper emphasizes the need for early biopsy of suspicious lesions presenting in areas in which physical examination is limited. Recommendations are made for handling the biopsy specimen when malignant lymphoma is suspected, as well as for the evaluation of local and distant sites. The role of surgery is primarily diagnostic in patients with malignant lymphoma.
Author List
Duncavage JA, Campbell BH, Hanson GA, Kun LE, Hansen RM, Toohill RJ, Malin TCAuthor
Bruce H. Campbell MD Emeritus Professor in the Otolaryngology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Aged
Biopsy
Female
Frontal Sinus
Humans
Lymphoma
Male
Maxillary Sinus
Middle Aged
Nasal Cavity
Nasopharyngeal Neoplasms
Neoplasm Staging
Nose Neoplasms
Paranasal Sinus Neoplasms
Tomography, X-Ray Computed
