Mean Platelet Volume: A Novel Predictor for Bone Erosion in Gouty Arthritis? Ann Clin Lab Sci 2019 Sep;49(5):661-665
Date
10/16/2019Pubmed ID
31611211Scopus ID
2-s2.0-85073180692 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
OBJECTIVE: Gout is a type of inflammatory arthritis that can be complicated with bone erosion through several inflammatory factors. Mean platelet volume (MPV) is regarded as a marker in many inflammatory disorders, but despite this, the metric has not been used for gout.
MATERIAL AND METHODS: This study evaluates the relationship between MPV and bone erosion in patients with gout. In total, 299 patients were evaluated retrospectively, and 120 patients were ultimately included based on inclusion criteria.
RESULTS: Both the duration of this disease and mean platelet volume were related to bone erosion in gout and may be regarded as independent predictors of bone erosion.
CONCLUSION: These results suggest that mean platelet volume can be a predictor of bone erosion in gout.
Author List
Zhang Q, Ke J, Zhou J, Li Z, Chen Y, Gao K, Zhang Y, Xie Y, Ma LAuthor
Qishuo Zhang MD Assistant Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ArthritisBone and Bones
Female
Gout
Humans
Male
Mean Platelet Volume
Middle Aged
Multivariate Analysis
Regression Analysis