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Influence of dietary vitamin E on platelet thromboxane A2 and vascular prostacyclin I2 in rabbit. Prostaglandins Leukot Med 1982 Oct;9(4):373-8

Date

10/01/1982

Pubmed ID

6757965

DOI

10.1016/0262-1746(82)90093-2

Abstract

Rabbits were maintained on vitamin E-deficient and vitamin E-supplemented diets. Thrombin- and collagen-induced thromboxane A2 production were significantly elevated in vitamin E-deficient platelets. Conversion of arachidonic acid to platelet thromboxane A2 was unchanged between the two groups of animals. Prostacyclin I2 production in the aortas from vitamin E-deficient rabbits was significantly elevated.

Author List

Pritchard KA Jr, Karpen CW, Merola AJ, Panganamala RV

Author

Kirkwood A. Pritchard PhD Professor in the Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

6-Ketoprostaglandin F1 alpha
Animals
Aorta, Thoracic
Blood Platelets
Diet
Dinoprostone
Epoprostenol
Prostaglandins E
Rabbits
Thromboxane A2
Thromboxanes
Vitamin E
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a