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Psychosocial Stressors and Telomere Length: A Current Review of the Science. Annu Rev Public Health 2020 Apr 02;41:223-245

Date

01/05/2020

Pubmed ID

31900099

DOI

10.1146/annurev-publhealth-040119-094239

Scopus ID

2-s2.0-85082933448 (requires institutional sign-in at Scopus site)   78 Citations

Abstract

A growing literature suggests that exposure to adverse social conditions may accelerate biological aging, offering one mechanism through which adversity may increase risk for age-related disease. As one of the most extensively studied biological markers of aging, telomere length (TL) provides a valuable tool to understand potential influences of social adversity on the aging process. Indeed, a sizeable literature now links a wide range of stressors to TL across the life span. The aim of this article is to review and evaluate this extant literature with a focus on studies that investigate psychosocial stress exposures and experiences in early life and adulthood. We conclude by outlining potential biological and behavioral mechanisms through which psychosocial stress may influence TL, and we discuss directions for future research in this area.

Author List

Rentscher KE, Carroll JE, Mitchell C

Author

Kelly E. Rentscher PhD Assistant Professor in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Adult Survivors of Child Abuse
Aged
Aged, 80 and over
Aging
Child
Child Abuse
Child, Preschool
Female
Humans
Life Change Events
Male
Middle Aged
Stress, Psychological
Telomere Shortening
Young Adult