Predicting cumulative incidence probability by direct binomial regression Biometrika We suggest a new simple approach for estimation and assessment of covariate effects for the cumulative incidence curve in the competing risks model. We consider a semiparametric regression model where some effects may be time-varying and some may be constant over time. Our estimator can be implemented by standard software. Our simulation study shows that the estimator works well and has finite-sample properties comparable with the subdistribution approach. We apply the method to bone marrow tran
Date
03/01/2008Abstract
We suggest a new simple approach for estimation and assessment of covariate effects for the cumulative incidence curve in the competing risks model. We consider a semiparametric regression model where some effects may be time-varying and some may be constant over time. Our estimator can be implemented by standard software. Our simulation study shows that the estimator works well and has finite-sample properties comparable with the subdistribution approach. We apply the method to bone marrow transplant data and estimate the cumulative incidence of death in complete remission following a bone marrow transplantation. Here death in complete remission and relapse are two competing events.
Author List
Scheike TH, Zhang MJ and Gerds TAAuthor
Mei-Jie Zhang PhD Professor in the Institute for Health and Equity department at Medical College of WisconsinView Online