Team triathlon effects on physiological, psychological, and immunological measures in women breast cancer survivors. Support Care Cancer 2020 Dec;28(12):6095-6104
Date
04/22/2020Pubmed ID
32314053DOI
10.1007/s00520-020-05457-2Scopus ID
2-s2.0-85084088106 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
PURPOSE: Exercise after breast cancer diagnosis and treatment improves cancer-related outcomes, although the mechanisms involved are not clear. This study evaluated the impact of exercise on body composition, strength, endurance, quality of life (QOL), fatigue, and endocrine and inflammatory biomarkers in breast cancer survivors participating in a highly monitored, clinically supervised, moderate-intensity exercise program. The association of hormonal and inflammatory biomarkers with the observed physiological changes was assessed.
METHODS: Female breast cancer survivors (BCS; n = 46) who engaged in a goal-oriented 14-week triathlon exercise training program were compared to an untrained control group of female BCS (n = 16). Psychosocial metrics, QOL, cancer-related fatigue, and exercise self-efficacy were evaluated via pre- and post-exercise intervention questionnaires. Serum estradiol and inflammatory biomarkers (C-reactive protein (CRP), sTNFR1a, estradiol, leptin, and adiponectin) were measured prior to the exercise training program start and after the completion of the goal triathlon.
RESULTS: After exercise training, the exercise group had lower BMI and arm circumferences. Greater positive change was noted in the trained group for QOL, fatigue, and self-efficacy questionnaires. Functional endurance improved in the trained but not the control group. Knee and elbow strength were not different between the groups, except that knee flexion at 180 degrees∙sec-1 was higher in trained. The only significantly different biomarker was adiponectin, which decreased in the trained group.
CONCLUSIONS: Group triathlon exercise training may be beneficial to BCS by significantly improving their psychosocial measures, functional endurance, and BMI.
Author List
Tjoe JA, Piacentine LB, Papanek PE, Raff H, Richards J, Harkins AL, Yin J, Ng AVAuthors
Alexander V. Ng PhD Associate Professor in the Exercise Science department at Marquette UniversityPaula Papanek PhD, MPT, LAT, FACSM Associate Professor & Director of Exercise Science in the Exercise Science & Physical Therapy department at Marquette University
Linda Piacentine BS,MS,NP,PhD Assistant Professor in the College of Nursing department at Marquette University
Hershel Raff PhD Professor in the Academic Affairs department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultAged
Breast Neoplasms
Cancer Survivors
Cooperative Behavior
Cytokines
Exercise
Exercise Therapy
Fatigue
Female
Hormones
Humans
Inflammation
Middle Aged
Peer Group
Physical Conditioning, Human
Quality of Life
Surveys and Questionnaires
