Carotid baroreceptor reflex regulation of forearm vascular resistance in man. J Physiol 1983 Apr;337:655-64
Date
04/01/1983Pubmed ID
6875950Pubmed Central ID
PMC1199130DOI
10.1113/jphysiol.1983.sp014647Scopus ID
2-s2.0-0020646057 (requires institutional sign-in at Scopus site) 27 CitationsAbstract
The carotid baroreflex regulation of forearm vascular resistance in man is uncertain. Forearm vascular resistance, blood pressure and R-R interval responses to carotid sinus stimulation were therefore measured in seven healthy men. Carotid stimuli were delivered by gradually applying neck pressure, neck suction or neck suction during simultaneous low-level lower-body negative pressure. Mean arterial blood pressure and R-R interval responses to neck suction and pressure were immediate and were sustained throughout the periods of stimulation. In contrast, forearm vascular responses, were transient. During simultaneous mild lower-body negative pressure (which decreases cardiopulmonary baroreceptor stimulation and increases forearm vascular resistance), neck-suction-induced forearm vasodilation was exaggerated and sustained throughout the entire period of neck suction. There was a linear relationship between the level of resting forearm vascular resistance and the change in resistance produced by carotid stimuli. It is concluded that reflex changes in forearm vascular resistance provoked by carotid baroreceptor stimuli are immediate and evanescent in man. Simultaneous reduction of cardiopulmonary baroreceptor activity heightens the magnitude and duration of forearm vasodilation induced by carotid baroreceptor stimulation.
Author List
Ebert TJAuthor
Thomas J. Ebert MD, PhD Adjunct Professor in the Anesthesiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Adaptation, PhysiologicalAdult
Blood Pressure
Carotid Sinus
Forearm
Humans
Lower Body Negative Pressure
Male
Pressoreceptors
Pressure
Reflex
Time Factors
Vascular Resistance
