Faculty Collaboration Database

Feasibility of applying the 2day deferral for repeat plateletpheresis: Indian perspective. Transfus Apher Sci 2013 Jun;48(3):341-3

Date

05/07/2013

Pubmed ID

23643473

DOI

10.1016/j.transci.2013.04.013

Scopus ID

2-s2.0-84878866189 (requires institutional sign-in at Scopus site)   6 Citations

Abstract

As the use of single donor apheresis platelets and plateletpheresis procedures done steadily increases in India, the plateletpheresis donors are at an increased risk of postpheresis anemia and thrombocytopenia. This study was planned in order to evaluate the effect of plateletpheresis on the hematological parameters in the local donor population and to evaluate the possibility of following the 2day deferral for repeat plateletpheresis. A total of 60 plateletpheresis procedures performed over a period of 1year with CS 3000 Plus Baxter Fenwal were evaluated. All the post-donation hematological parameters showed a significant decrease from the pre-donation values (p<0.001). Post-donation hemoglobin <12g, which is defined by WHO as anemia irrespective of the gender occurred in 25% (n=15) of the donors. The post-donation platelet count was less than 100×10(9)/L in 16.6% (n=10) of the procedure. The ability of these donors to serve as repeat plateletpheresis donor after 2days as recommended by AABB needs to be evaluated by further studies done post donation. Keeping in view the hematological profile of our donor population we recommend that donors who already have a low or borderline pre-donation platelet count and hemoglobin should be assessed and monitored post-donation for decrements in these parameters. While serving as repeat donors, their pre donation hemoglobin and platelet counts should be tested again.

Author List

Nomani L, Raina TR, Sidhu M

Author

Laila Nomani MD Assistant Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Anemia
Blood Donors
Feasibility Studies
Hematocrit
Hemoglobins
Humans
India
Leukocytes
Male
Middle Aged
Platelet Count
Plateletpheresis
Time Factors
Young Adult