Systemic Lupus Erythematosus, Evans Syndrome, and Neurofibromatosis: An Unusual Combination in Pediatric Patient. J Pediatr Hematol Oncol 2020 May;42(4):e244-e247
Date
04/30/2019Pubmed ID
31033790DOI
10.1097/MPH.0000000000001490Scopus ID
2-s2.0-85064910643 (requires institutional sign-in at Scopus site) 1 CitationAbstract
Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organ systems. Patients can have hematologic manifestations, including Evans syndrome (ES), which is characterized by immune-mediated thrombocytopenia and anemia. The association of neurofibromatosis 1 (NF1) with autoimmune disorders is rarely reported. We will review the literature for this combination of disorders and describe a case of a 16-year-old girl who presents with immune-mediated cytopenias and is diagnosed with SLE, ES, and NF1. There are 7 reported cases of SLE and NF1 and only 2 are pediatric cases. There are no reports of the combination of SLE, ES, and NF1.
Author List
Moskop A, Dalrymple A, Dolatshahi LAuthor
Amy Moskop MD Assistant Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAnemia, Hemolytic, Autoimmune
Female
Humans
Lupus Erythematosus, Systemic
Neurofibromatosis 1
Thrombocytopenia
