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Evaluation of lithium therapy for alcoholism. J Clin Psychiatry 1984 Dec;45(12):494-9

Date

12/01/1984

Pubmed ID

6389520

Scopus ID

2-s2.0-0021718345 (requires institutional sign-in at Scopus site)   41 Citations

Abstract

The efficacy of lithium therapy for alcoholism was examined in 84 alcoholic volunteers admitted for rehabilitation. Subjects were randomly assigned to a lithium or placebo treatment condition for 18 months, and were reinterviewed monthly to document their compliance, drinking status, and mood. Two separate factors contributed to abstinent outcome: therapeutic serum lithium levels (greater than or equal to 0.4 mEq/L) and medication compliance. Recommendations are proposed for studying compliance effects in future treatment studies.

Author List

Fawcett J, Clark DC, Gibbons RD, Aagesen CA, Pisani VD, Tilkin JM, Sellers D, Stutzman D

Author

David C. Clark PhD Assistant Dean, Professor in the Research Office department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Alcoholism
Clinical Trials as Topic
Depressive Disorder
Female
Humans
Lithium
Male
Middle Aged
Patient Compliance
Placebos
Psychiatric Status Rating Scales
Random Allocation
Recurrence