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Rosai-Dorfman Disease: Rare Presentation as Isolated Mediastinal and Hilar Lymphadenopathy. Cureus 2018 Jan 02;10(1):e2017

Date

03/14/2018

Pubmed ID

29531870

Pubmed Central ID

PMC5837302

DOI

10.7759/cureus.2017

Abstract

Rosai-Dorfman disease (RDD) is a rare, benign, and predominantly nodal disease that most commonly presents as bilateral, painless cervical lymphadenopathy; although inguinal, axillary, mediastinal, and hilar lymphadenopathy has also been reported. Apart from nodal involvement, RDD has extranodal manifestations involving bone, soft tissue, and liver as well as constitutional symptoms of fever, night sweats, and weight loss, which make it reasonable to rule out the infectious, autoimmune, and malignant conditions as the differential diagnosis. We herein report a case of RDD affecting only the mediastinal and hilar region in an 83-year-old woman.

Author List

Lateef N, Haseeb A, Ghori UK, Tauseef A, Dawood M, Hasan Kazmi SM

Author

Uzair K. Ghori MD Assistant Professor in the Medicine department at Medical College of Wisconsin




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