Faculty Collaboration Database

Intracranial Capillary Hemangiomas: A Peripartum Presentation and Review of the Literature. World Neurosurg 2021 Jan;145:220-228

Date

09/14/2020

Pubmed ID

32920159

DOI

10.1016/j.wneu.2020.09.032

Scopus ID

2-s2.0-85092451059 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

BACKGROUND: Intracranial capillary hemangiomas (ICHs) are rare vascular tumors composed of a bed of many narrow thin-walled vessels. Within the confines of the skull, these tumors can lead to serious neurologic deficits including cranial nerve dysfunction, mood/personality disturbances, and signs of intracranial mass effect.

METHODS: We report the case of a 23-year-old, 5-week postpartum woman with a history of progressive painful ophthalmalgia of the right eye presenting with rapid onset of ptosis, diplopia, and right-sided facial pain and hypesthesia. Imaging demonstrated a small extraaxial mass within the right cavernous sinus. She underwent 2 operations via an endoscopic endonasal approach for biopsy followed by complete resection. Histology showed a highly mitotic capillary hemangioma, which was negative for both estrogen and progesterone receptors.

RESULTS: We review cases of ICH reported in the literature and provide an updated summary of the presentation, diagnosis, and treatment of ICH. We then present a brief analysis of the reported cases with respect to age and sex.

CONCLUSIONS: We conclude that, in experienced hands, the endoscopic endonasal approach can be used to access the cavernous sinus for complete resection of ICHs of the cavernous sinus. We also suggest that further attention be paid to such cases in pregnant and peripartum women as these tumors may progress more quickly in this subpopulation.

Author List

Massman LJ, Conteh F, Cochran EJ, Zwagerman NT

Authors

Elizabeth J. Cochran MD Adjunct Professor in the Pathology department at Medical College of Wisconsin
Nathan Zwagerman MD Associate Professor in the Neurosurgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Biopsy
Brain Neoplasms
Endoscopy
Female
Hemangioma, Capillary
Hemangioma, Cavernous, Central Nervous System
Humans
Magnetic Resonance Imaging
Nasal Cavity
Neurosurgical Procedures
Pain
Postpartum Period
Pregnancy
Pregnancy Complications, Neoplastic
Treatment Outcome
Young Adult