Pediatric patients with orofacial granulomatosis likely to subsequently develop intestinal Crohn's disease: Brief Report. Pediatr Dermatol 2020 Nov;37(6):1162-1164
Date
09/29/2020Pubmed ID
32985729DOI
10.1111/pde.14390Scopus ID
2-s2.0-85091614814 (requires institutional sign-in at Scopus site) 3 CitationsAbstract
Orofacial granulomatosis (OFG) is an uncommon chronic granulomatous condition presenting as perioral inflammation in the absence of systemic disease. There is continued debate regarding whether OFG is a distinct clinical disorder or a manifestation of orofacial Crohn's disease. Our retrospective review identified 7 patients diagnosed with OFG between 2000 and 2018 at a tertiary pediatric hospital. Four of the 7 patients subsequently developed Crohn's disease with a median delay of 3.1 years (range 0.4-6.9 years). This indicates that gastroenterology evaluation with long-term monitoring for intestinal Crohn's disease is warranted.
Author List
Chen KL, Diiorio DA, Chiu YE, Sokumbi OAuthor
Yvonne E. Chiu MD Vice Chair, Professor in the Dermatology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ChildCrohn Disease
Granulomatosis, Orofacial
Humans
Inflammation
Retrospective Studies
Tertiary Care Centers
