Effect of direct thrombin inhibition with Bivalirudin (Hirulog) on restenosis after coronary angioplasty. Am J Cardiol 1998 Aug 15;82(4):511-5
Date
09/02/1998Pubmed ID
9723642DOI
10.1016/s0002-9149(98)00371-3Scopus ID
2-s2.0-0031848588 (requires institutional sign-in at Scopus site) 29 CitationsAbstract
The direct antithrombin, bivalirudin, did not reduce angiographic restenosis measured either as the dichotomous restenosis rate of 62% for bivalirudin and 58% for heparin (p = 0.70), or as the late loss in lumen diameter of 0.44 +/- 0.47 mm for bivalirudin and 0.39 +/- 0.53 mm for heparin (p = 0.62). Direct thrombin inhibition with bivalirudin neither reduces angiographic restenosis nor alters the impact of several established risk factors for restenosis.
Author List
Burchenal JE, Marks DS, Tift Mann J, Schweiger MJ, Rothman MT, Ganz P, Adelman B, Bittl JAAuthor
David S. Marks MD Vice Chair, Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAged
Angioplasty, Balloon, Coronary
Antithrombins
Coronary Disease
Female
Heparin
Hirudin Therapy
Hirudins
Humans
Linear Models
Male
Middle Aged
Peptide Fragments
Radiography
Recombinant Proteins
Recurrence
Risk Factors
Treatment Outcome