A comparison of functional MR activation patterns during silent and audible language tasks. AJNR Am J Neuroradiol 1995 May;16(5):1087-92
Date
05/01/1995Pubmed ID
7639132Pubmed Central ID
PMC8337795Scopus ID
2-s2.0-0029068901 (requires institutional sign-in at Scopus site) 147 CitationsAbstract
PURPOSE: To compare word generation tasks performed silently and aloud as paradigms for functional MR.
METHODS: Images were obtained at 1.5 T, with echoplanar acquisition in nine subjects performing word generation aloud or silently. Functional images created from the echoplanar images by means of cross-correlation techniques were superimposed on anatomic reference images. The location of activation from the two tasks was tabulated; the number of activated pixels in each region from the two tasks was compared.
RESULTS: Both silent and aloud word generation produced activation in the inferior frontal lobes, sensorimotor cortex regions, supplementary motor areas, and anterior cingulate gyri, predominantly in the dominant hemisphere. Significantly more activated pixels and fewer artifacts were detected with silent word generation than with word generation aloud.
CONCLUSION: Word generation silently or aloud produce activation in the brain. Greater activation can be detected in the left frontal lobe with silent word generation, although the subject's performance of the task cannot be monitored independently during silent word generation.
Author List
Yetkin FZ, Hammeke TA, Swanson SJ, Morris GL, Mueller WM, McAuliffe TL, Haughton VMAuthors
Timothy L. McAuliffe PhD Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinWade M. Mueller MD Professor in the Neurosurgery department at Medical College of Wisconsin
Sara J. Swanson PhD Chief, Professor in the Neurology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultArousal
Brain Mapping
Cerebral Cortex
Dominance, Cerebral
Female
Humans
Magnetic Resonance Imaging
Male
Reference Values
Thinking
Verbal Behavior
