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Bone Marrow Suppression Associated With Celiac Disease in a 4-Year-Old Boy. ACG Case Rep J 2021 Feb;8(2):e00538



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Celiac disease is an immune-mediated process against gluten, resulting in inflammation and villous atrophy of the duodenum. Symptoms of malabsorption characterize the classic presentation; however, abdominal pain, constipation, and nutritional deficiencies can also be seen. We present a case of a 4-year-old boy who was found to have celiac disease after presenting with diarrhea, abdominal pain, weight loss, and new-onset pancytopenia. Symptoms resolved, and laboratory values normalized after the initiation of a gluten-free diet, indicating the bone marrow suppression was due to celiac disease, which needs to be considered when hematologic abnormalities are present, even in the absence of gastrointestinal symptoms.

Author List

Watson A, Kolinski J, Suchi M, Elkadri A


Abdul Aziz Elkadri MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
Julie M. Kolinski MD Associate Professor in the Medicine department at Medical College of Wisconsin
Mariko Suchi MD, PhD Associate Professor in the Pathology department at Medical College of Wisconsin