Ocular toxicity of hydroxychloroquine. Semin Ophthalmol 2008;23(3):201-9
Date
04/25/2008Pubmed ID
18432546DOI
10.1080/08820530802049962Scopus ID
2-s2.0-42449150064 (requires institutional sign-in at Scopus site) 87 CitationsAbstract
This review summarizes the current literature regarding the ocular complications of hydroxychloroquine. Hydroxychloroquine has been used since the 1950s for the treatment of various rheumatic and dermatologic diseases. Hydroxychloroquine can cause ocular toxicity, with the most serious being an irreversible retinopathy. At the present time, no "gold standard" exists for identification of the ocular toxicity prior to its development. This has led to controversy regarding the recommendations for ophthalmologic examinations for screening patients on hydroxychloroquine.
Author List
Tehrani R, Ostrowski RA, Hariman R, Jay WMAuthor
Richard Hariman MD Associate Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AntimalarialsAntirheumatic Agents
Electroretinography
Fluorescein Angiography
Humans
Hydroxychloroquine
Incidence
Retinal Diseases
Risk Factors
Visual Fields