Ventricular CSF shunt infections associated with Corynebacterium jeikeium: report of three cases and review. Clin Infect Dis 1993 Jan;16(1):139-41
Date
01/01/1993Pubmed ID
8448291DOI
10.1093/clinids/16.1.139Scopus ID
2-s2.0-0027498350 (requires institutional sign-in at Scopus site) 27 CitationsAbstract
Ventricular CSF shunt infections due to Corynebacterium jeikeium are rare. Such infections may become manifest weeks to months after surgery. They are difficult to eradicate and often recur. We report three cases of C. jeikeium ventricular CSF shunt infections, all of which occurred in patients who received long-term prophylactic therapy with antibiotics and had protracted hospitalizations. Two patients had multiple recurrences, and all patients required shunt revision. Additional therapy with intrathecal vancomycin for 6-10 days after surgery was effective for this unusual cause of ventricular CSF shunt infection. On the basis of our experience and a review of six previously published case reports, we recommend CSF sterilization with intravenous and intrathecal vancomycin, followed by replacement of shunt hardware.
Author List
Greene KA, Clark RJ, Zabramski JMAuthor
Karl A. Greene MD Adjunct Assistant Professor in the Neurosurgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAged
Aged, 80 and over
Cerebrospinal Fluid Shunts
Child
Corynebacterium Infections
Female
Humans
Male
