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Electroencephalography resting-state networks in people with Stroke. Brain Behav 2021 May;11(5):e02097

Date

03/25/2021

Pubmed ID

33759382

Pubmed Central ID

PMC8119848

DOI

10.1002/brb3.2097

Scopus ID

2-s2.0-85102860499 (requires institutional sign-in at Scopus site)   22 Citations

Abstract

INTRODUCTION: The purpose of this study was to characterize resting-state cortical networks in chronic stroke survivors using electroencephalography (EEG).

METHODS: Electroencephalography data were collected from 14 chronic stroke and 11 neurologically intact participants while they were in a relaxed, resting state. EEG power was normalized to reduce bias and used as an indicator of network activity. Correlations of orthogonalized EEG activity were used as a measure of functional connectivity between cortical regions.

RESULTS: We found reduced cortical activity and connectivity in the alpha (p < .05; p = .05) and beta (p < .05; p = .03) bands after stroke while connectivity in the gamma (p = .031) band increased. Asymmetries, driven by a reduction in the lesioned hemisphere, were also noted in cortical activity (p = .001) after stroke.

CONCLUSION: These findings suggest that stroke lesions cause a network alteration to more local (higher frequency), asymmetric networks. Understanding changes in cortical networks after stroke could be combined with controllability models to identify (and target) alternate brain network states that reduce functional impairment.

Author List

Snyder DB, Schmit BD, Hyngstrom AS, Beardsley SA

Authors

Scott Beardsley PhD Associate Professor in the Biomedical Engineering department at Marquette University
Allison Hyngstrom PhD Associate Professor in the Physical Therapy department at Marquette University
Brian Schmit PhD Professor in the Biomedical Engineering department at Marquette University




MESH terms used to index this publication - Major topics in bold

Brain
Brain Mapping
Electroencephalography
Humans
Stroke