Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Initial Clinical Experience of MR-Guided Radiotherapy for Non-Small Cell Lung Cancer. Front Oncol 2021;11:617681

Date

03/30/2021

Pubmed ID

33777759

Pubmed Central ID

PMC7988221

DOI

10.3389/fonc.2021.617681

Scopus ID

2-s2.0-85103051459 (requires institutional sign-in at Scopus site)   23 Citations

Abstract

Curative-intent radiotherapy plays an integral role in the treatment of lung cancer and therefore improving its therapeutic index is vital. MR guided radiotherapy (MRgRT) systems are the latest technological advance which may help with achieving this aim. The majority of MRgRT treatments delivered to date have been stereotactic body radiation therapy (SBRT) based and include the treatment of (ultra-) central tumors. However, there is a move to also implement MRgRT as curative-intent treatment for patients with inoperable locally advanced NSCLC. This paper presents the initial clinical experience of using the two commercially available systems to date: the ViewRay MRIdian and Elekta Unity. The challenges and potential solutions associated with MRgRT in lung cancer will also be highlighted.

Author List

Crockett CB, Samson P, Chuter R, Dubec M, Faivre-Finn C, Green OL, Hackett SL, McDonald F, Robinson C, Shiarli AM, Straza MW, Verhoeff JJC, Werner-Wasik M, Vlacich G, Cobben D

Author

Michael W. Straza MD, PhD Assistant Professor in the Radiation Oncology department at Medical College of Wisconsin