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Post-Covid-19 Cholangiopathy-A New Indication for Liver Transplantation: A Case Report. Transplant Proc 2021 May;53(4):1132-1137

Date

04/14/2021

Pubmed ID

33846012

Pubmed Central ID

PMC7953456

DOI

10.1016/j.transproceed.2021.03.007

Scopus ID

2-s2.0-85103958333 (requires institutional sign-in at Scopus site)   51 Citations

Abstract

Liver injury is one of the nonpulmonary manifestations described in coronavirus disease 2019 (COVID-19). Post-COVID-19 cholangiopathy is a special entity of liver injury that has been suggested as a variant of secondary sclerosing cholangitis in critically ill patients (SSC-CIP). In the general population, the outcome of SSC-CIP has been reported to be poor without orthotopic liver transplantation (OLT). However, the role of OLT for post-COVID-19 cholangiopathy is unknown. We present a case report of a 47-year-old man who recovered from acute respiratory distress syndrome from COVID-19 and subsequently developed end-stage liver disease from post-COVID-19 cholangiopathy. The patient underwent OLT and is doing well with normal liver tests for 7 months. To our knowledge, this is the first case report of a patient who underwent successful liver transplantation for post-COVID-19 cholangiopathy.

Author List

Durazo FA, Nicholas AA, Mahaffey JJ, Sova S, Evans JJ, Trivella JP, Loy V, Kim J, Zimmerman MA, Hong JC

Authors

Joohyun Kim MD, PhD Associate Professor in the Surgery department at Medical College of Wisconsin
Veronica Loy DO Associate Professor in the Medicine department at Medical College of Wisconsin
Jennifer J. Mahaffey APP System Dir Outpatient in the Surgery department at Medical College of Wisconsin
Juan Pablo Trivella MD Assistant Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

End Stage Liver Disease
Humans
Liver
Liver Transplantation
Male
Middle Aged