Post-Covid-19 Cholangiopathy-A New Indication for Liver Transplantation: A Case Report. Transplant Proc 2021 May;53(4):1132-1137
Date
04/14/2021Pubmed ID
33846012Pubmed Central ID
PMC7953456DOI
10.1016/j.transproceed.2021.03.007Scopus ID
2-s2.0-85103958333 (requires institutional sign-in at Scopus site) 53 CitationsAbstract
Liver injury is one of the nonpulmonary manifestations described in coronavirus disease 2019 (COVID-19). Post-COVID-19 cholangiopathy is a special entity of liver injury that has been suggested as a variant of secondary sclerosing cholangitis in critically ill patients (SSC-CIP). In the general population, the outcome of SSC-CIP has been reported to be poor without orthotopic liver transplantation (OLT). However, the role of OLT for post-COVID-19 cholangiopathy is unknown. We present a case report of a 47-year-old man who recovered from acute respiratory distress syndrome from COVID-19 and subsequently developed end-stage liver disease from post-COVID-19 cholangiopathy. The patient underwent OLT and is doing well with normal liver tests for 7 months. To our knowledge, this is the first case report of a patient who underwent successful liver transplantation for post-COVID-19 cholangiopathy.
Author List
Durazo FA, Nicholas AA, Mahaffey JJ, Sova S, Evans JJ, Trivella JP, Loy V, Kim J, Zimmerman MA, Hong JCAuthors
Joohyun Kim MD, PhD Associate Professor in the Surgery department at Medical College of WisconsinVeronica Loy DO Associate Professor in the Medicine department at Medical College of Wisconsin
Jennifer J. Mahaffey APP Outpatient in the Obstetrics and Gynecology department at Medical College of Wisconsin
Juan Pablo Trivella MD Assistant Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
End Stage Liver DiseaseHumans
Liver
Liver Transplantation
Male
Middle Aged