Faculty Collaboration Database

Wagner-Meissner neurilemmoma of the right cheek. Ann Diagn Pathol 2008 Jun;12(3):204-7

Date

05/20/2008

Pubmed ID

18486897

DOI

10.1016/j.anndiagpath.2006.09.001

Scopus ID

2-s2.0-43449083754 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

We report a very rare case of Wagner-Meissner neurilemmoma in the cheek of a 10-year-old boy. The tumor presented as a slowly growing soft tissue swelling. Magnetic resonance imaging disclosed a very infiltrative, 9-cm mass involving the subcutis and deep soft tissues of the right cheek. Microscopically, the tumor was unencapsulated and composed almost entirely of well-formed Wagner-Meissner corpuscles that formed confluent sheets, perivascular cuffs, and individual corpuscles percolating through adipose tissue. Compared with the 3 previous reports, which describe circumscribed, encapsulated tumors in adult patients, this case had distinctive clinicopathologic features never reported: presentation in a pediatric patient, location in the head and neck region, and an infiltrative growth pattern.

Author List

Wu AJ, Jarzembowski J, Morag Y, Lucas DR

Author

Jason A. Jarzembowski MD, PhD Sr Associate Dean, CEO CSG, Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Biomarkers, Tumor
Cheek
Child
Facial Neoplasms
Humans
Magnetic Resonance Imaging
Male
Mechanoreceptors
Neurilemmoma
S100 Proteins
Soft Tissue Neoplasms