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Exposures in the Indoor Environment and Prevalence of Allergic Conditions in the United States of America. Int J Environ Res Public Health 2021 May 06;18(9)

Date

06/03/2021

Pubmed ID

34066511

Pubmed Central ID

PMC8124238

DOI

10.3390/ijerph18094945

Scopus ID

2-s2.0-85105220713 (requires institutional sign-in at Scopus site)   9 Citations

Abstract

Our study examines the association of the presence of mildew, cockroaches, and pets in homes as well as household dust allergens with the prevalence and/or severity of allergic diseases. No study has concurrently assessed home environment exposures in relation to allergic conditions in the general US population. Data from 5409 participants from the 2005-2006 National Health and Nutrition Examination Survey (NHANES) living in their current homes for ≥one year were analyzed. Multivariate logistic regression analyses between home exposures and allergic diseases prevalence and severity were performed. In adjusted analyses, mildew was associated with higher current asthma, allergies, and allergic rhinitis prevalence; endotoxin, with higher current asthma prevalence; and dust Canis familiaris (Can f) 1, with higher allergic rhinitis prevalence. However, presence of cockroaches and dust Dermatophagoides farinae (Der f) 1 were associated, respectively, with lower current asthma and allergies prevalence. Presence of mildew, dust Der f1, Dermatophagoides pteronyssinus (Der p) 1, Felis domesticus (Fel d) 1, and endotoxin were all associated with asthma and/or wheeze severity. Non-atopic asthma was more frequent with mildew and/or musty smell dust and higher dust Fel d1 concentration, while atopic asthma was more prevalent with higher Can f1 and endotoxin concentrations in dust. This study confirms previous relationships and reports novel associations, generating hypotheses for future research.

Author List

Gasana J, Ibrahimou B, Albatineh AN, Al-Zoughool M, Zein D

Author

Janvier Gasana MD, MPH, PhD Adjunct Associate Professor in the Institute for Health and Equity department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Air Pollution, Indoor
Allergens
Animals
Cats
Dogs
Dust
Humans
Hypersensitivity
Nutrition Surveys
Prevalence
United States