Medical College of Wisconsin
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Automated image processing pipeline for adaptive optics scanning light ophthalmoscopy. Biomed Opt Express 2021 Jun 01;12(6):3142-3168

Date

07/06/2021

Pubmed ID

34221651

Pubmed Central ID

PMC8221964

DOI

10.1364/BOE.418079

Scopus ID

2-s2.0-85106351305 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

To mitigate the substantial post-processing burden associated with adaptive optics scanning light ophthalmoscopy (AOSLO), we have developed an open-source, automated AOSLO image processing pipeline with both "live" and "full" modes. The live mode provides feedback during acquisition, while the full mode is intended to automatically integrate the copious disparate modules currently used in generating analyzable montages. The mean (±SD) lag between initiation and montage placement for the live pipeline was 54.6 ± 32.7s. The full pipeline reduced overall human operator time by 54.9 ± 28.4%, with no significant difference in resultant cone density metrics. The reduced overhead decreases both the technical burden and operating cost of AOSLO imaging, increasing overall clinical accessibility.

Author List

Salmon AE, Cooper RF, Chen M, Higgins B, Cava JA, Chen N, Follett HM, Gaffney M, Heitkotter H, Heffernan E, Schmidt TG, Carroll J

Authors

Joseph J. Carroll PhD Director, Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin
Robert F. Cooper Ph.D Assistant Professor in the Biomedical Engineering department at Marquette University
Taly Gilat-Schmidt PhD Associate Professor of Biomedical Engineering in the Biomedical Engineering department at Marquette University