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Asymptomatic reopening of ductus arteriosus after successful closure by indomethacin in premature infants. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1993 Sep-Oct;34(5):379-84

Date

09/01/1993

Pubmed ID

8237357

Abstract

Indomethacin has been demonstrated to be effective for closure of hemodynamically symptomatic patent ductus arteriosus (PDA) in premature infants. The five cases in this study had acquired asymptomatic reopening of PDA a long time after successful closure by oral indomethacin. Providing adequate oxygen, giving another course of indomethacin, preventing excessive fluid intake and keeping hematocrit level greater than 40% had been tried to close the ducti but all in vain. However, most could be expected to close spontaneously later. Herein, the possible contributing factors and the treatment rationale are discussed.

Author List

Yen SL, Teng RJ, Ho MM

Author

Ru-Jeng Teng MD Associate Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Ductus Arteriosus, Patent
Female
Humans
Indomethacin
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases
Male
Recurrence
jenkins-FCD Prod-478 d1509cf07a111124a2d122fd3df854cc0b993c00