Surgical outcomes and survival rates of colon cancer in children and young adults. Am J Surg 2021 Apr;221(4):718-724
Date
03/09/2021Pubmed ID
33678398DOI
10.1016/j.amjsurg.2021.02.010Scopus ID
2-s2.0-85102032449 (requires institutional sign-in at Scopus site) 9 CitationsAbstract
INTRODUCTION: Colon cancer in children and young adults is rare. We sought to compare outcomes and survival between patients ≤and>25 years of age with colon cancer.
METHODS: Using the National Cancer Database, patients with colon cancer between 2004 and 2016 were identified. We included patients with histological codes consistent with invasive colon adenocarcinoma and excluded those missing data about treatment. Post-surgical outcomes and survival were compared.
RESULTS: Of 531,462 patients meeting criteria, 947 were ≤25 years. Patients ≤25 had more advanced disease (stage III:44.4%vs33.4%, stage IV:27.5%vs.15.3%) and higher rates of total colectomy (8.9%vs.2.7%) and proctocolectomy (5.0%vs.0.0%) than those >25 years. Stage for stage, 5-year survival was higher in patients ≤25 than those >25years. On multivariate regression, age was not associated with increased risk of mortality while male sex and uninsured status were.
CONCLUSIONS: Despite presenting with more advanced disease, patients ≤25 years with colon cancer had better survival than those >25 years.
Author List
Akinkuotu AC, Maduekwe UN, Hayes-Jordan AAuthor
Ugwuji N. Maduekwe MD Associate Dean, Associate Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Aged
Child
Colonic Neoplasms
Female
Humans
Male
Middle Aged
Neoplasm Staging
Risk Factors
Survival Rate
