Does acral lentiginous melanoma subtype account for differences in patterns of care in Black patients? Am J Surg 2021 Apr;221(4):706-711
Date
01/20/2021Pubmed ID
33461732Pubmed Central ID
PMC8376182DOI
10.1016/j.amjsurg.2020.12.040Scopus ID
2-s2.0-85100196770 (requires institutional sign-in at Scopus site) 8 CitationsAbstract
BACKGROUND: Melanoma-specific outcomes for Black patients are worse when compared to non-Hispanic white (NHW) patients. We sought to evaluate whether acral lentiginous melanoma, seen more commonly in Black patients, was associated with racial disparities in outcomes METHODS: The National Cancer Database was analyzed for major subtypes of stage I-IV melanoma diagnosed from 2004 to 2016. The association between Black race and (Siegel et al., Jan) 1 acral melanoma diagnosis and (Bradford et al., Apr) 2 receipt of major amputation for surgical management of melanoma was evaluated using multivariable logistic regression.
RESULTS: 251,864 patients were included (1453 Black). Black patients had increased odds of acral melanoma (odds ratio [OR] = 27.6, 95% CI]: 24.4, 31.2) compared to NHW patients. Black patients still had higher odds ratios of major amputation across all stages after adjusting for acral histology and other potential confounders CONCLUSIONS: Increased prevalence of acral melanoma in Black patients does not fully account for increased receipt of major amputation.
Author List
Carter TM, Strassle PD, Ollila DW, Stitzenberg KB, Meyers MO, Maduekwe UNAuthor
Ugwuji N. Maduekwe MD Associate Dean, Associate Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedFemale
Humans
Lymphatic Metastasis
Male
Melanoma
Middle Aged
Neoplasm Staging
Prognosis
Skin Neoplasms
Survival Analysis
