Faculty Collaboration Database

Small bowel myoelectric activity in peritonitis. Am J Surg 1993 Jun;165(6):681-5

Date

06/01/1993

Pubmed ID

8506966

DOI

10.1016/s0002-9610(05)80787-1

Scopus ID

2-s2.0-0027179366 (requires institutional sign-in at Scopus site)   7 Citations

Abstract

Peritonitis is associated clinically with paralytic ileus, but the physiologic mechanisms of the effects of peritonitis on bowel myoelectric activity have not been explored. Bipolar electrodes were inserted into the rats, and myoelectric control recordings were obtained for 4 h/d for 5 consecutive days. Peritonitis was then induced, and myoelectric recordings were again obtained. Each animal served as its own control. Prior to induction of peritonitis (control), phase I, II, and III myoelectric activity was present in all recordings. The cycle duration of the migrating myoelectric complex was 17.17 +/- 0.39 minutes, and the migration velocity of phase III was 0.61 +/- 0.02 cm/min. The most striking feature during peritonitis was the complete inhibition of phase II activity. Phase III activity, however, was present with a cycle duration of 16.69 +/- 0.42 minutes. This study shows that some features of intestinal myoelectric activity (phase III) are preserved during episodes of peritonitis, and others are changed (phase I) or lost (phase II). Disappearance of phase II activity in this type of ileus emphasizes its importance in normal small bowel motility.

Author List

Frantzides CT, Mathias C, Ludwig KA, Edmiston CE, Condon RE

Author

Kirk A. Ludwig MD Chief, Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Bacteroides fragilis
Electromyography
Escherichia coli
Gastrointestinal Motility
Intestine, Small
Male
Peritonitis
Rats
Rats, Sprague-Dawley