Small bowel myoelectric activity in peritonitis. Am J Surg 1993 Jun;165(6):681-5
Date
06/01/1993Pubmed ID
8506966DOI
10.1016/s0002-9610(05)80787-1Scopus ID
2-s2.0-0027179366 (requires institutional sign-in at Scopus site) 7 CitationsAbstract
Peritonitis is associated clinically with paralytic ileus, but the physiologic mechanisms of the effects of peritonitis on bowel myoelectric activity have not been explored. Bipolar electrodes were inserted into the rats, and myoelectric control recordings were obtained for 4 h/d for 5 consecutive days. Peritonitis was then induced, and myoelectric recordings were again obtained. Each animal served as its own control. Prior to induction of peritonitis (control), phase I, II, and III myoelectric activity was present in all recordings. The cycle duration of the migrating myoelectric complex was 17.17 +/- 0.39 minutes, and the migration velocity of phase III was 0.61 +/- 0.02 cm/min. The most striking feature during peritonitis was the complete inhibition of phase II activity. Phase III activity, however, was present with a cycle duration of 16.69 +/- 0.42 minutes. This study shows that some features of intestinal myoelectric activity (phase III) are preserved during episodes of peritonitis, and others are changed (phase I) or lost (phase II). Disappearance of phase II activity in this type of ileus emphasizes its importance in normal small bowel motility.
Author List
Frantzides CT, Mathias C, Ludwig KA, Edmiston CE, Condon REAuthor
Kirk A. Ludwig MD Chief, Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsBacteroides fragilis
Electromyography
Escherichia coli
Gastrointestinal Motility
Intestine, Small
Male
Peritonitis
Rats
Rats, Sprague-Dawley