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Hemolysis after subcutaneous deoxycholic acid overdose. Am J Emerg Med 2022 Feb;52:268.e1-268.e2

Date

08/31/2021

Pubmed ID

34456101

DOI

10.1016/j.ajem.2021.08.021

Scopus ID

2-s2.0-85113786357 (requires institutional sign-in at Scopus site)

Abstract

This report describes a case of hemolysis in a patient injecting deoxycholic acid and benzyl alcohol for aesthetic benefit without medical supervision. The concentration and dose injected by the patient resulted in a 10-fold overdose of deoxycholic acid in comparison to the FDA-recommended dosing for the approved indication. Providers should be aware of medically unsupervised use of DCA and other injectables and the potential risks associated with this practice.

Author List

Sharpe A, O'Keefe M, Windsor K, Theobald J, Feldman R

Authors

Ryan J. Feldman PharmD Adjunct Assistant Professor in the School of Pharmacy Administration department at Medical College of Wisconsin
Jillian Lee Theobald MD, PhD Associate Professor in the Emergency Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Cholagogues and Choleretics
Deoxycholic Acid
Hemolysis
Humans
Injections, Subcutaneous
Male