Psychosocial correlates of atrial natriuretic peptide: a marker of vascular health. Ann Behav Med 2013 Feb;45(1):99-109
Date
09/22/2012Pubmed ID
22996638DOI
10.1007/s12160-012-9414-1Scopus ID
2-s2.0-84873409237 (requires institutional sign-in at Scopus site) 5 CitationsAbstract
BACKGROUND: Psychosocial factors have been associated with cardiovascular outcomes, but few studies have examined the association between psychosocial function and natriuretic peptides.
PURPOSE: The purpose of this study is to determine the predictive value of hostility, anger, and social support in relation to atrial natriuretic peptide (ANP), a marker of vascular health, among middle-aged men.
METHODS: One hundred twenty-one men (mean age = 39.8 years, SD = 4.1) underwent assessments of ANP and completed the Cook-Medley Hostility Scale, the Spielberger State-Trait Anger Scale, and the Interview Schedule for Social Interaction.
RESULTS: Higher levels of hostility (β = 0.22 [95 % CI 0.04, 0.40], P = 0.032) and trait anger (β = 0.18 [95 % CI 0.01, 0.37], P = 0.044) were associated with greater ANP levels. In contrast, higher perceived social support was also associated with lower ANP levels, (β = -0.19 [95 % CI -0.05, -0.41], P = 0.010).
CONCLUSIONS: Psychosocial factors, including hostility, anger, and social support, are associated with varying ANP levels among middle-aged men, independent of cardiovascular and behavioral risk factors.
Author List
Smith P, Tuomisto MT, Blumenthal J, Sherwood A, Parkkinen L, Kähönen M, Pörsti I, Majahalme S, Turjanmaa VAuthor
Silja Majahalme MD, PhD Associate Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAnger
Atrial Natriuretic Factor
Biomarkers
Blood Pressure
Cholesterol
Hostility
Humans
Hypertension
Male
Middle Aged
Personality Inventory
Risk Factors
Social Support
