Faculty Collaboration Database

Frequency shift in baroregulatory oscillation in borderline hypertensive subjects. Am J Hypertens 1997 May;10(5 Pt 1):500-4

Date

05/01/1997

Pubmed ID

9160759

DOI

10.1016/s0895-7061(96)00490-6

Scopus ID

2-s2.0-0030986355 (requires institutional sign-in at Scopus site)   10 Citations

Abstract

The aim of this study was to quantify the frequency shift in vasomotor oscillations in blood pressure we observed in borderline hypertensive individuals in our previous study. Electrocardiogram and intraarterial blood pressure were recorded in 33 normotensive, 29 borderline hypertensive, and 33 mildly hypertensive men (aged 35 to 45 years). Five-minute stationary periods in supine, sitting, and standing positions, and during sleep were extracted from the recordings for autoregressive frequency domain analysis. In borderline hypertensive subjects vasomotor oscillations in the range of 0.05 to 0.12 Hz in blood pressure and heart rate, assumed to be associated with baroreceptor activity, were shifted to lower values as compared with the other two groups. The frequency shift was assessed by median frequency of the oscillations. Significant between-group differences were observed in the supine and sitting positions. No significant between-group differences were seen in normalized spectral power estimates. Further studies are required to determine whether the frequency shift provides prognostic information on cardiovascular morbidity.

Author List

Takalo R, Korhonen I, Turjanmaa V, Majahalme S, Tuomisto M, Uusitalo A

Author

Silja Majahalme MD, PhD Associate Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Biological Clocks
Blood Pressure
Electrocardiography
Electromyography
Heart Rate
Humans
Hypertension
Male
Middle Aged
Pressoreceptors
Vasomotor System