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Radiographic and clinical outcomes in cavernous carotid fistula with special focus on alternative transvenous access techniques. J Clin Neurosci 2015 May;22(5):859-64

Date

02/16/2015

Pubmed ID

25682541

DOI

10.1016/j.jocn.2014.11.006

Scopus ID

2-s2.0-84927176289 (requires institutional sign-in at Scopus site)   22 Citations

Abstract

Carotid cavernous fistulae (CCF) are dangerous entities that may cause progressive cranial neuropathy, headache and blindness. Endovascular therapy for CCF is the treatment of choice and can be accomplished with minimal morbidity, but optimal treatment strategies vary according to CCF anatomy. We aimed to define a tailored endovascular treatment algorithm for CCF with a focus on traditional and aberrant venous anatomy. Retrospective cohort analysis of data for 57 patients (age range, 18-90 years, mean 53 years) with CCF (35 direct, 22 indirect) was performed. Treatment was transarterial (n=31), transvenous (n=18), combined (n=2), or observation (n=6). Non-conventional transvenous access (that is, via the facial vein, pterygoid plexus, or via direct puncture of the inferior ophthalmic or frontal vein) was employed in five patients. Mean follow-up period was 12 months. Radiographic cure rate in treated CCF was 96%. Forty-five patients presented with ophthalmic symptoms (chemosis, proptosis, eye pain); all resolved within 6 weeks of successful treatment. Forty-three patients presented with cranial nerve III, IV and/or VI palsy; complete recovery was seen in 54% and partial recovery in 18%. Five patients presented with blindness and five with declining visual acuity. No patient with blindness regained sight after treatment, but all five patients with declining vision recovered some visual acuity. The complication rate was 10.6% (one transient abducens nerve palsy, two symptomatic cerebral infarctions, and three groin hematomas). The permanent complication rate was 3.5%. Multimodal treatment of CCF, including non-traditional routes of transvenous access, results in excellent outcomes and low morbidity.

Author List

Morton RP, Tariq F, Levitt MR, Nerva JD, Mossa-Basha M, Sekhar LN, Kim LJ, Hallam DK, Ghodke BV

Author

John D. Nerva MD Assistant Professor in the Neurosurgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Abducens Nerve Diseases
Adolescent
Adult
Aged
Aged, 80 and over
Blindness
Carotid-Cavernous Sinus Fistula
Cohort Studies
Cranial Nerve Diseases
Embolization, Therapeutic
Endovascular Procedures
Exophthalmos
Female
Humans
Jugular Veins
Male
Middle Aged
Radiography
Retrospective Studies
Treatment Outcome
Young Adult