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Interferon therapy for orbital infiltration secondary to Erdheim-Chester disease. Am J Ophthalmol 2001 Dec;132(6):945-7

Date

12/04/2001

Pubmed ID

11730673

DOI

10.1016/s0002-9394(01)01141-2

Scopus ID

2-s2.0-0035205734 (requires institutional sign-in at Scopus site)   50 Citations

Abstract

PURPOSE: To describe a 55-year-old male with Erdheim-Chester disease with bilateral orbital infiltration and visual loss who was successfully treated with interferon-alpha.

METHODS: Interventional case report.

RESULTS: The patient was treated with interferon-alpha and had an improvement in his clinical signs, including his visual acuity, after 4 weeks of interferon therapy.

CONCLUSION: Interferon-alpha can be effective in the treatment of orbital infiltration secondary to Erdheim-Chester disease.

Author List

Esmaeli B, Ahmadi A, Tang R, Schiffman J, Kurzrock R

Author

Razelle Kurzrock MD Center Associate Director, Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Exophthalmos
Granuloma
Histiocytosis, Non-Langerhans-Cell
Humans
Interferon-alpha
Magnetic Resonance Imaging
Male
Middle Aged
Orbital Diseases
Osteosclerosis
Radionuclide Imaging
Technetium Tc 99m Medronate
Visual Acuity
Xanthomatosis