Faculty Collaboration Database

Mycobacterial pulmonary infections after allogeneic bone marrow transplantation. Am J Med 1984 Jul;77(1):35-40

Date

07/01/1984

Pubmed ID

6430082

DOI

10.1016/0002-9343(84)90432-7

Scopus ID

2-s2.0-0021252125 (requires institutional sign-in at Scopus site)   59 Citations

Abstract

Allogeneic bone marrow transplant recipients are prone to pulmonary infections caused by a wide spectrum of organisms. Nonetheless, the recognition of lung disease caused by Mycobacterium tuberculosis in two patients and Mycobacterium avium-intracellulare in a third patient at the University of Texas M. D. Anderson Hospital represents the first report of these agents occurring in allogeneic marrow recipients. Diagnosis can be difficult due to atypical presentations, initial negative culture results, and the presence of more than one pathogen in these compromised hosts. In the case involving Mycobacterium avium-intracellulare infection, culture of material obtained by bronchoscopy established the diagnosis when repeated sputum samples showed no growth. A vigorous search for mycobacteria is suggested in allogeneic bone marrow transplant recipients with pulmonary infections.

Author List

Kurzrock R, Zander A, Vellekoop L, Kanojia M, Luna M, Dicke K

Author

Razelle Kurzrock MD Center Associate Director, Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Bone Marrow Transplantation
Bronchoscopy
Humans
Male
Mycobacterium avium
Mycobacterium tuberculosis
Postoperative Complications
Radiography
Transplantation, Homologous
Tuberculosis, Pulmonary