Obstructive lung disease after allogeneic bone marrow transplantation. Transplantation 1984 Feb;37(2):156-60
Date
02/01/1984Pubmed ID
6364498DOI
10.1097/00007890-198402000-00008Scopus ID
2-s2.0-0021322372 (requires institutional sign-in at Scopus site) 27 CitationsAbstract
We report the cases of 3 patients with marked dyspnea and an obstructive ventilation disorder associated with chronic graft-versus-host disease after allogeneic bone marrow transplantation. This disorder was characterized by recurrent pulmonary infections and colonization of the lower respiratory tract by Pseudomonas aeruginosa. Two patients have shown rapidly progressive deterioration with death following due to respiratory failure. Intensive therapy with antibiotics, bronchodilators, high-dose steroids, and azathioprine was not effective in arresting the malignant course of this disorder.
Author List
Kurzrock R, Zander A, Kanojia M, Vellekoop L, Spitzer G, Jagannath S, Schell S, Peters L, Dicke KAuthor
Razelle Kurzrock MD Center Associate Director, Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultBone Marrow Transplantation
Graft vs Host Disease
Humans
Lung Diseases, Obstructive
Male
Pseudomonas Infections
Respiratory Function Tests
Respiratory Tract Infections
Smoking
Transplantation, Homologous
Whole-Body Irradiation
