Faculty Collaboration Database

Gout prevalence in the Hmong: a prime example of health disparity and the role of community-based genetic research. Per Med 2021 May;18(3):311-327

Date

04/01/2021

Pubmed ID

33787318

DOI

10.2217/pme-2020-0107

Scopus ID

2-s2.0-85104685672 (requires institutional sign-in at Scopus site)   10 Citations

Abstract

Individuals of distinct Asian backgrounds are commonly aggregated as Asian, which could mask the differences in the etiology and prevalence of health conditions in the different Asian subgroups. The Hmong are a growing Asian subgroup in the United States with a higher prevalence of gout and gout-related comorbidities than non-Hmong. Genetic explorations in the Hmong suggest a higher prevalence of genetic polymorphisms associated with an increased risk of hyperuricemia and gout. History of immigration, acculturation, lifestyle factors, including dietary and social behavioral patterns, and the use of traditional medicines in the Hmong community may also increase the risk of developing gout and lead to poor gout management outcomes. Engaging minorities such as the Hmong population in biomedical research is a needed step to reduce the burden of health disparities within their respective communities, increase diversity in genomic studies, and accelerate the adoption of precision medicine to clinical practice.

Author List

Roman YM, Lor K, Xiong T, Culhane-Pera K, Straka RJ

Author

Kajua B. Lor PharmD Chair, Associate Professor in the School of Pharmacy Administration department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Age of Onset
Aged
Chronic Disease
Community-Based Participatory Research
Female
Genetic Research
Gout
Health Behavior
Health Status Disparities
Health Surveys
Humans
Hyperuricemia
Life Style
Male
Middle Aged
Minnesota