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Prominent inflammatory changes on muscle biopsy in patients with Miyoshi myopathy. Neuromuscul Disord 1999 Oct;9(6-7):417-20

Date

11/02/1999

Pubmed ID

10545047

DOI

10.1016/s0960-8966(99)00041-3

Scopus ID

2-s2.0-0032884692 (requires institutional sign-in at Scopus site)   41 Citations

Abstract

Miyoshi myopathy is a rare autosomal recessive distal myopathy characterized by early and prominent involvement of the posterior compartment of the legs. We describe two patients with the clinical diagnosis of Miyoshi myopathy who demonstrated marked inflammatory changes on muscle biopsy of clinically less affected muscles. This report illustrates the importance of recognizing the marked variability in histopathology of Miyoshi myopathy which may include an inflammatory infiltrate on muscle biopsy which mimics the histopathologic picture of an inflammatory myopathy.

Author List

Rowin J, Meriggioli MN, Cochran EJ, Sanders DB

Author

Elizabeth J. Cochran MD Adjunct Professor in the Pathology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Biopsy
Female
Fibrosis
Humans
Inflammation
Male
Muscle, Skeletal
Muscular Dystrophies