Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Living related small bowel transplantation: donor surgical technique. Ann Surg 2004 Nov;240(5):779-84

Date

10/20/2004

Pubmed ID

15492558

Pubmed Central ID

PMC1356482

DOI

10.1097/01.sla.0000143266.59408.d7

Scopus ID

2-s2.0-7044246092 (requires institutional sign-in at Scopus site)   68 Citations

Abstract

OBJECTIVE: To describe a standardized technique for ileal graft procurement in the setting of living related bowel transplantation.

SUMMARY BACKGROUND DATA: Living donor transplantation has been successfully developed for kidney, liver, pancreas, and lung transplantation. More recently, living related small bowel transplantation (LR-SBTx) has been developed with the aim of expanding the pool of intestinal graft donors and reducing the mortality in patients on the waiting list. To date, a total of 25 LR-SBTx worldwide have been reported to the international registry. We herein report the largest single center experience.

METHODS: A segment of ileum, 150 to 200 cm, is resected 20 cm proximal to the ileocecal valve (ICV), which is always preserved. The arterial inflow is given by the terminal branch of the superior mesenteric artery and venous outflow by a proximal segment of the superior mesenteric vein. The entire bowel is measured intraoperatively and at least 60% of intestine length is left in the donor.

RESULTS: Since 1998, we have performed 9 terminal ileum resections for small bowel donation. None of the donors has experienced persistent alteration of bowel habits or malabsorption; only 1 minor wound complication has occurred.

CONCLUSIONS: Terminal ileal resection with preservation of the ICV seems to assure fast functional recovery of the donor and has minimal postoperative complications.

Author List

Testa G, Panaro F, Schena S, Holterman M, Abcarian H, Benedetti E

Author

Stefano Schena MD, PhD Associate Professor in the Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Female
Humans
Ileum
Living Donors
Male
Middle Aged
Tissue and Organ Harvesting