Instrumental validation of percutaneous transmyocardial revascularization: follow-up data at one year. Ann Thorac Surg 2000 Sep;70(3):1115-8
Date
10/04/2000Pubmed ID
11016391DOI
10.1016/s0003-4975(00)01791-4Scopus ID
2-s2.0-0033807509 (requires institutional sign-in at Scopus site) 6 CitationsAbstract
BACKGROUND: Despite the clinical efficacy of percutaneous transmyocardial revascularization (PTMR), up to date there are still no instrumental validations to demonstrate both the improved perfusion of treated areas and cardiac function.
METHODS: During the first year of follow-up after PTMR, 27 patients (group A) underwent 99mTc MIBI exercise-single photon emission tomography (SPET), while 30 patients (group B) underwent serial transthoracic echocardiography (TTE) evaluations with analysis of cardiac volumes and subendocardial layer thickness in systole.
RESULTS: All 57 patients had a significant angina Canadian Cardiovascular Society (CCS) class improvement. Group A patients (75%) had improved exercise-SPET perfusion in treated areas at 12 weeks after PTMR, and at the next follow-up. Group B patients had non-significant reduction in global volume and no significant change in ejection fraction. However, there was an improvement in thickness of the subendocardial-treated areas in systole that persisted during follow-up.
CONCLUSIONS: The use of SPET and TTE validates the clinical efficacy of PTMR.
Author List
Bortone AS, D'Agostino D, Schena S, Rubini G, Viecca M, Sardaro V, Tucci A, de Luca Tupputi Schinosa LAuthor
Stefano Schena MD, PhD Associate Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedEchocardiography
Female
Follow-Up Studies
Humans
Male
Middle Aged
Minimally Invasive Surgical Procedures
Myocardial Revascularization
Technetium Tc 99m Sestamibi
Tomography, Emission-Computed, Single-Photon