Rapid Exome and Genome Sequencing in the Intensive Care Unit. Crit Care Clin 2022 Apr;38(2):173-184
Date
04/05/2022Pubmed ID
35369941DOI
10.1016/j.ccc.2021.11.001Scopus ID
2-s2.0-85127316826 (requires institutional sign-in at Scopus site) 5 CitationsAbstract
Rapid genomic sequencing has become a powerful diagnostic tool for critically ill children. Accumulated data support clinical utility. Advances in sequencing technology have improved reliability of rapid results and reduced turnaround times. Cost savings to health care institutions are not only the result of reduced sequencing charges (which have paralleled advances in sequencing technology), but also and more specifically have impact on diagnosis-specific medical management and reduced length of hospitalization. The use of genomic sequencing in critical care is still primarily limited to academic centers but will ultimately become the wider-spread standard of care for select patients.
Author List
Muriello M, Basel DAuthors
Donald Basel MD Chief, Professor in the Pediatrics department at Medical College of WisconsinMichael Muriello MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
ChildExome
Genetic Testing
Humans
Intensive Care Units
Reproducibility of Results
