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Small cell carcinoma of the urinary bladder: Distinctive cytological characteristics and Cyto-histologic correlation. Ann Diagn Pathol 2022 Aug;59:151947

Date

04/16/2022

Pubmed ID

35427925

DOI

10.1016/j.anndiagpath.2022.151947

Scopus ID

2-s2.0-85127923115 (requires institutional sign-in at Scopus site)

Abstract

Preoperative diagnosis in liquid-based cytology preparation in voided urine specimen and cyto-histologic correlation of small cell carcinoma of the urinary bladder has not been described in detail in the literature. A 79-year old male presented at our institution with gross hematuria. He was accurately diagnosed with small cell carcinoma of the bladder on liquid-based cytology in urine. The patient subsequently proceeded to transurethral resection of the bladder tumor, confirming the diagnosis. In this article, we present a detailed report of primary urothelial carcinoma with dominant neuroendocrine differentiation of the bladder describing the cytologic and histologic morphologic features, its differential diagnosis with a review of the literature.

Author List

Puzyrenko A, Nomani L, Iczkowski K, Giorgadze T

Authors

Tamara Giorgadze MD Professor in the Pathology department at Medical College of Wisconsin
Laila Nomani MD Assistant Professor in the Pathology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aged
Carcinoma, Small Cell
Carcinoma, Transitional Cell
Cytodiagnosis
Humans
Male
Urinary Bladder
Urinary Bladder Neoplasms