Thoracoabdominal Normothermic Regional Perfusion for Cardiac Procurement. ASAIO J 2022 Oct 01;68(10):e163-e165
Date
04/20/2022Pubmed ID
35439176DOI
10.1097/MAT.0000000000001749Scopus ID
2-s2.0-85131605578 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
In donation after circulatory death donors, warm ischemia time is a significant threat to successful cardiac transplantation. The ability to perfuse these organs during the minutes after death, until cardiac evaluation is completed to satisfaction, is crucial in limiting total warm ischemic time. Thoracoabdominal normothermic regional perfusion (TANRP) has emerged as a promising strategy for recovering and monitoring these hearts. We propose a series of clinical practice pearls that we follow for all donation after circulatory death procurements to streamline the process of setting up a TANRP circuit and ensuring all team members present at time procurement are familiar with the procedure. Bicaval cannulation is achieved via the abdomen for aortic cannulation, and via the chest for right atrial cannulation, avoiding deairing maneuvers and providing the shortest possible duration from incision to initiation of cardiopulmonary bypass. Here, we describe a series of practice techniques which we have utilized in our early experience with TANRP.
Author List
Joyce DL, Carlson SF, Kohmoto T, Durham L, Ubert A, Candek C, Koerten D, Joyce LDAuthors
Lucian A. Durham MD, PhD Associate Professor in the Surgery department at Medical College of WisconsinTakushi Kohmoto MD, PhD Professor in the Surgery department at Medical College of Wisconsin
H Adam Ubert MD Assistant Professor in the Surgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Heart TransplantationHumans
Organ Preservation
Perfusion
Tissue Donors
Tissue and Organ Procurement
Warm Ischemia
