Functional magnetic resonance imaging of human auditory cortex. Ann Neurol 1994 Jun;35(6):662-72
Date
06/01/1994Pubmed ID
8210222DOI
10.1002/ana.410350606Scopus ID
2-s2.0-0028358402 (requires institutional sign-in at Scopus site) 358 CitationsAbstract
Magnetic resonance imaging methods recently demonstrated regional cerebral signal changes in response to limb movement and visual stimulation, attributed to blood flow enhancement. We studied 5 normal subjects scanned while listening to auditory stimuli including nonspeech noise, meaningless speech sounds, single words, and narrative text. Imaged regions included the lateral aspects of both hemispheres. Signal changes in the superior temporal gyrus and superior temporal sulcus were observed bilaterally in all subjects. Speech stimuli were associated with significantly more widespread signal changes than was the noise stimulus, while no consistent differences were observed between responses to different speech stimuli. Considerable intersubject variability in the topography of signal changes was observed. These observations confirm the utility of magnetic resonance imaging in the study of human brain structure-function relationships and emphasize the role of the superior temporal gyrus in perception of acoustic-phonetic features of speech, rather than processing of semantic features.
Author List
Binder JR, Rao SM, Hammeke TA, Yetkin FZ, Jesmanowicz A, Bandettini PA, Wong EC, Estkowski LD, Goldstein MD, Haughton VMAuthor
Jeffrey R. Binder MD Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Acoustic StimulationAdult
Auditory Cortex
Brain
Brain Mapping
Female
Functional Laterality
Humans
Language
Magnetic Resonance Imaging
Male
Noise
Organ Specificity
Speech
Time Factors
