Medical College of Wisconsin
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Rate sensitivity of blood pressure to hypoxia. J Theor Biol 1985 Feb 21;112(4):839-45

Date

02/21/1985

Pubmed ID

3999765

DOI

10.1016/s0022-5193(85)80065-5

Scopus ID

2-s2.0-0021852963 (requires institutional sign-in at Scopus site)

Abstract

A biochemical kinetic model is used to describe changes in mean arterial blood pressure in dogs to three different rates of fall of arterial partial pressure of oxygen. The model is a linear loop with one variable rate coefficient (parametric control) which has been previously shown to characterize the rate sensitivity to presented stimuli. A three component model was identified under a least squares criterion and it showed that a unique (stimulation independent) representation can be obtained which can serve as a conceptual framework for the study of this phenomenon.

Author List

Licko V, Raff H

Author

Hershel Raff PhD Professor in the Academic Affairs department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Blood Pressure
Dogs
Hypoxia
Mathematics
Models, Cardiovascular
Oxygen
Partial Pressure