Rate sensitivity of blood pressure to hypoxia. J Theor Biol 1985 Feb 21;112(4):839-45
Date
02/21/1985Pubmed ID
3999765DOI
10.1016/s0022-5193(85)80065-5Scopus ID
2-s2.0-0021852963Abstract
A biochemical kinetic model is used to describe changes in mean arterial blood pressure in dogs to three different rates of fall of arterial partial pressure of oxygen. The model is a linear loop with one variable rate coefficient (parametric control) which has been previously shown to characterize the rate sensitivity to presented stimuli. A three component model was identified under a least squares criterion and it showed that a unique (stimulation independent) representation can be obtained which can serve as a conceptual framework for the study of this phenomenon.
Author List
Licko V, Raff HAuthor
Hershel Raff PhD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsBlood Pressure
Dogs
Hypoxia
Mathematics
Models, Cardiovascular
Oxygen
Partial Pressure
