Faculty Collaboration Database

Magnetic tagging of therapeutic cells for MRI. J Nucl Med 2009 Feb;50(2):171-4

Date

01/24/2009

Pubmed ID

19164242

Pubmed Central ID

PMC2633027

DOI

10.2967/jnumed.108.053546

Scopus ID

2-s2.0-59249103743 (requires institutional sign-in at Scopus site)   68 Citations

Abstract

Transplantation of stem cells or immune cells has shown promise for the treatment of several diseases. Monitoring magnetically labeled cells with MRI has furthered our understanding of cellular migration and the pathophysiology of diseases in experimental models. These studies should pave the way for guiding clinical trials using cell-based therapies. This review briefly describes the various methods used to label and track cells with MRI and the potential for such methods to translate to human applications.

Author List

Budde MD, Frank JA

Author

Matthew Budde PhD Associate Professor in the Neurosurgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Contrast Media
Ferric Compounds
Fluorocarbons
Gadolinium
Genes, Reporter
Humans
Immune System
Magnetic Resonance Imaging
Magnetics
Metal Nanoparticles
Stem Cell Transplantation
Transplants